Gene

kcnc2

ID

ZDB-GENE-070410-118

Name

potassium voltage-gated channel, Shaw-related subfamily, member 2

Symbol

kcnc2 Nomenclature History

Previous Names

zgc:162956

Type

protein_coding_gene

Location

Chr: 4 Mapping Details/Browsers

Description

Predicted to have delayed rectifier potassium channel activity. Predicted to be involved in potassium ion transmembrane transport. Predicted to localize to several cellular components, including dendrite membrane; neuronal cell body membrane; and voltage-gated potassium channel complex. Orthologous to human KCNC2 (potassium voltage-gated channel subfamily C member 2).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

No data available

Cross-Species Comparison

High Throughput Data

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

No data available

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With kcnc2 Human Ortholog

Disease Ontology Term	Multi-Species Data	OMIM Term	OMIM Phenotype ID
developmental and epileptic encephalopathy 103	Alliance	Developmental and epileptic encephalopathy 103	619913

Associated With kcnc2 Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR000210	BTB/POZ domain
Domain	IPR003131	Potassium channel tetramerisation-type BTB domain
Domain	IPR005821	Ion transport domain
Family	IPR003968	Potassium channel, voltage dependent, Kv
Family	IPR003974	Potassium channel, voltage dependent, Kv3
Homologous_superfamily	IPR011333	SKP1/BTB/POZ domain superfamily
Homologous_superfamily	IPR027359	Voltage-dependent channel domain superfamily

Domain Details Per Protein

Protein	Length	BTB/POZ domain	Ion transport domain	Potassium channel tetramerisation-type BTB domain	Potassium channel, voltage dependent, Kv	Potassium channel, voltage dependent, Kv3	SKP1/BTB/POZ domain superfamily	Voltage-dependent channel domain superfamily
UniProtKB:A0A8M2BBM3 InterPro	593
UniProtKB:A0A8M6YXW1 InterPro	572
UniProtKB:A0A8M3B8P1 InterPro	589
UniProtKB:E0R7P8 InterPro	597

Transcripts

Genome Browsers

Type	Name	Annotation Method	Length (nt)	Analysis
mRNA	kcnc2-201 (1) Ensembl	Ensembl	1,797 nt	Select Tool ZFIN BLAST
mRNA	kcnc2-202 (1) Ensembl	Ensembl	700 nt	Select Tool ZFIN BLAST
mRNA	kcnc2-204 (1) Ensembl	Ensembl	1,787 nt	Select Tool ZFIN BLAST
mRNA	kcnc2-205 (1) Ensembl	Ensembl	1,314 nt	Select Tool ZFIN BLAST
ncRNA	kcnc2-003 (1) Ensembl	Ensembl	852 nt	Select Tool ZFIN BLAST

Interactions and Pathways

No data available

Antibodies

No data available

Plasmids

No data available

Constructs

Marker Relationships

Sequences

Orthology

Comparative Orthology: Alliance
Gene Tree: Ensembl

Citations